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Impaired neurocognitive function among HIV-infected Thais on stable antiretroviral therapy for more than 7 years

Author(s): A Avihingsanon | W Maek-a-nantawat | P Sithinamsuwan | J Ananworanich | S Suksawak | N Saysombut | W Charoenporn | P Phanuphak | V Valcour

Journal: Journal of the International AIDS Society ISSN 1758-2652
Volume: 15; Issue: 6(Suppl 4); Start page: 1; Date: 2012;
Original page

ABSTRACT
Background: There are limited data on HIV-associated neurocognitive disorders (HANDs) from resource-constraint region and few studies have firm documentation of duration of treatment and suppression of plasma virus. This study aimed to estimate the prevalence of HIV-related cognitive deterioration among HIV-infected patients who were on stable ART and to describe the pattern of neurocognitive impairment (NCI), daily life disturbance and associated factors. Methods: This was a cross-sectional evaluation of cognition in a sample of HIV adults at HIV-NAT, the Thai Red Cross AIDS Research Centre with data captured over a 6-month period. The Montreal Cognitive Assessment (MoCA), International HIV Dementia Scale (IHDS) and Activities of Daily Living Questionnaire (ADLQ) scale were administered. NCI was defined as a score of ≤10 on the IHDS or